Maresh's Tumor
His tumor is surrounded by arteries and veins (blood vessels for you medical types).
He'll probably need a specific type of surgeon, a vascular surgeon (specialist surgeon who works around blood vessels and nerves) to remove the tumor.
If his tumor is also wrapped around major nerves, his vascular surgeon may partner the surgery with a neurosurgeon.
The size of his tumor is fairly large. If this is removed, he's going to have an empty space inside his calf without any tissue.
When the surgical wound is closed and sewn shut they'll also have to close off this empty space.
Therefore, I wound think that he'll have a little "depression" when one looks at the outside of that part of his leg once he has his surgery.
If his tumor is removed without traumatizing his vascular and nervous system he should be able to play football eventually.
If not........